Volume EM Alignment Service
Full service for pre-processing large-scale 2D and 3D microscopy datasets.Robust Alignment, Registration, Stitching, Gradient Correction, and Normalization.
3D Alignment and Registration
Proper alignment of 3D electron microscopy image stacks is crucial for effective manual and automatic analysis. Overlapping regions are stitched together into a coherent dataset.
We offer a full service for the alignment of 3D electron microscopy datasets. Just upload the dataset and receive the results. No coding required.
Use Cases
Raw image acquisition by Francis Crick Institute
3D Alignment and Registration
Proper alignment of 3D electron microscopy image stacks is crucial for effective manual and automatic analysis. Overlapping regions are stitched together into a coherent dataset.
We offer a full service for the alignment of 3D electron microscopy datasets. Just upload the dataset and receive the results. No coding required.
2D In-Plane Stitching and Montages
Easily combine individual image tiles produced by your microscope into a single plane. Overlapping regions are stitched together with smart outlier rejection.
We offer a full service for the alignment of large-scale 2D electron microscopy or other images. Just upload the dataset and receive the results. No coding required.
Raw image acquisition by Carles Bosch, Francis Crick Institute
Raw image acquisition by Max Planck Institute for Brain Research
Normalization and Gradient Correction
Due to the sensitive nature of image acquisition, some artifacts are inevitable. Sections may show uneven brightness and contrast. There may be gradients across tiles or throughout the dataset.
Fortunately, these artifacts can be corrected using our technology. As part of our alignment and stitching services or separately, we offer services for normalization and gradient correction in large-scale datasets.
Stitching of 3D Tiles
Imaging large volumes with Micro-CT or Synchrotron X-Ray Tomography requires sub-dividing the volume into 3D tiles.
We offer services for stitching reconstructed tomography tiles into a coherent dataset.
Raw image data by Carles Bosch, Francis Crick Institute
Built for Life and Material Sciences
Benefits
Tried and true
Proven results for many large-scale EM datasets. Optimized for SBEM and serial-section SEM or TEM.
Fast Turnaround Times
Depending on the characteristics of your dataset, we are able to deliver results within days. More challenging datasets require a few weeks.
Delivery through WEBKNOSSOS
Browse and analyse your pre-processed datasets immediately in WEBKNOSSOS or export in a common data format.
Continuous Improvements
With every processed dataset, we improve our tooling to deliver even better results.